Harrold Hall was built in 1608 for Anne Farrar, who married Thomas Boteler, aged 15, in 1602, and who later took up the family seat at Biddenham, becoming Sir Thomas. In 1702 there were no Botelers in the male line, and Mary Boteler, one of three daughters, and heiress of Sir William Boteler, sold Harrold Hall to Anne Joliffe. She died in 1732, leaving the Hall to her niece, Anne Alston, daughter of Sir Roland Alston.

Anne Alston married Dr Richard Mead, well known for his "cure for the bite of a mad dog", i.e. rabies or hydrophobia, and they lived at Harrold Hall until her death in 1763. Dr Mead was undoubtedly a caring medical practitioner, physician to Royalty, and President of the Royal Society of Physicians. He had written many books, including one on poisons. He was aware that strictly enforced quarantine had kept the plague in bounds in Marseilles. In 1735 the Rev Benjamin Rogers of Carlton, who knew him well, repeated this cure .

Eventually, Harrold Hall, which was much enlarged in 1816, appears to have reverted to the Alstons, who sold it to Mr A C Beck, M.P. Harrold Hall was demolished in the early 1960s to make way for the Hall Close houses.